5-Alpha-Reductase Deficiency: Meaning and Development
5-alpha-reductase deficiency is an inherited variation that reduces conversion of testosterone into DHT and may affect genital development and puberty.
Gonadal Dysgenesis: Meaning, Types, and Health Effects
Gonadal dysgenesis is a variation in which the ovaries or testes develop incompletely, affecting hormones, puberty, fertility, or sex characteristics.
Hypospadias: Meaning, Types, Treatment, and Sexual Function
Hypospadias is a congenital variation in which the urethral opening develops on the underside of the penis rather than at the tip.
Micropenis: Meaning, Causes, Measurement, and Treatment
Micropenis is a medically measured penis that is substantially shorter than the expected range for a person’s age but is otherwise normally formed.
Androgen Insensitivity Syndrome: Meaning, Types, and Effects
Androgen insensitivity syndrome is a variation in which an XY body responds partly or not at all to testosterone and other androgens.
Congenital Adrenal Hyperplasia: Meaning, Types, and Effects
Congenital adrenal hyperplasia is an inherited group of conditions affecting adrenal hormone production, salt balance, growth, puberty, and sex development.
Klinefelter Syndrome: Meaning, Symptoms, and XXY Pattern
Klinefelter syndrome is a sex chromosome variation, usually involving an XXY pattern, that may affect testosterone, puberty, fertility, and development.
Turner Syndrome: Meaning, Symptoms, and Chromosome Pattern
Turner syndrome is a sex chromosome variation involving a missing, incomplete, or altered second sex chromosome in some or all cells.
Ovotesticular DSD: Meaning, Anatomy, and Development
Ovotesticular DSD is an intersex variation in which a person has both ovarian and testicular tissue, either separately or within an ovotestis.
Sex Chromosome Variation: Meaning, Types, and Examples
A sex chromosome variation is a natural difference in the number, structure, or arrangement of X or Y chromosomes, such as X, XXX, XXY, or XYY.